A two-vehicle crash on Highway 101 south of Orcutt left five people with serious injuries on Tuesday afternoon.
Shortly after noon, personnel from the Santa Barbara County Fire Department, the California Highway Patrol and American Medical Response were dispatched to the collision on northbound Highway 101 near Cat Canyon Road, fire Capt. Daniel Bertucelli said.
Additionally, a Calstar medical helicopter responded to the scene, landing on Cat Canyon Road to pick up one patient.
The T-bone crash reportedly happened when one vehicle struck the front side of the second car, Bertucelli said..
One patient had major injuries and was airlifted to Santa Barbara Cottage Hospital.
CHP officers from the Santa Maria area will investigate the circumstances surrounding the crash.